Subacute thyroiditis (its second name is thyroiditis de Kervena) is pathological changes in the inflammatory nature, consisting of damage to the thyroid gland and destruction of its cells.
This form of thyroiditis develops as a result of the introduction into the cells of the thyroid virus and the formation of foreign proteins. In response, the body reacts with the inflammatory process and the inclusion of autoimmune mechanisms with subsequent destruction of the gland cells synthroid news.
Often in a history of a patient with the onset of this disease, symptoms of a viral infection are present. The interval between the appearance of viral pathology and the development of subacute thyroiditis is approximately 3 weeks.
The onset of the disease is accompanied by the appearance of symptoms of weakness, fever, strong palpitation, pain in the area of the thyroid gland projections, which is enhanced by palpation.
Characteristic for this thyroiditis is also the appearance of signs of thyrotoxicosis. Symptomatically, this manifests itself in the form of weight loss, irritability, tearfulness. There is often also sweating and shortness of breath.
At palpation the thyroid gland in such patients is partially or completely increased due to the edema that is formed as a result of inflammation. Sometimes unpleasant sensations can radiate into the ears or jaw, thereby simulating otitis or toothache.
The primary symptoms of a subacute inflammation of the thyroid are similar to a Based's disease. But with Basedova's disease, hyperthyroidism is caused by increased production of hormones, and this process is increasing, and with subacute thyroiditis tissue destruction occurs with the release of T3 and T4 into the blood, and then signs of hyperthyroidism pass.
In response to the release of thyroid hormones by the feedback method, the function of the hypothalamus begins to be inhibited. Thus, the production of thyrotropin decreases. The remaining part of the thyroid gland begins to slow down its work and hypothyroidism occurs, accompanied by its characteristic symptoms. However, this does not last long and regulatory mechanisms, including, return the hormone level to the limits of the physiological norm.
Acute, or initial. It is characterized by the appearance of temperature, pain in the thyroid gland, symptoms of thyrotoxicosis.
Euthyroid. It begins when the supply of homonas from damaged cells is depleted, and signs of hyperthyroidism are replaced by a normal amount of hormones. With minor lesions, de Querwen's thyroiditis may persist for a long time at this stage, but with the involvement of a large section of the gland the following can develop.
Hypothyroid. Often accompanied by biochemical signs, and sometimes symptoms of reduced thyroid function. As the recovery and restoration of the structure of this body, everything comes back to normal.
Sometimes, in very severe subacute thyroiditis, thyroid function may not recover, but fortunately, it happens in very rare cases.